EDITORIAL

P. Anzenbacher and E. Anzenbacherová
Enzyme Systems of Detoxication – Overview of Recent Approaches

M. Stiborová, J. Hudeček, E. Frei and H.H. Schmeiser
Contribution of Biotransformation Enzymes to the Development of Renal Injury and Urothelial Cancer Caused by Aristolochic Acid: Urgent Questions, Difficult Answers

E. Horváthová
Trends in the Study of Genetic Susceptibility

M. Tichý, I. Hanzlíková, M. Rucki, A. Pokorná, R. Uzlová, J. Tumová
Acute Toxicity of Binary Mixtures: Alternative Methods, QSAR and Mechanisms

J. Kassa, J. Bajgar, K. Kuča, K. Musílek, J. Karasová
The Present Approaches to the Development of Prophylactic and Therapeutic Antidotes Against Nerve Agents

A. Korkmaz, D.X. Tan and R.J. Reiter
Acute and Delayed Sulfur Mustard Toxicity; Novel Mechanisms and Future Studies

E. Ujházy, J. Navarová, M. Dubovický, Š. Bezek, M. Mach
Important Issues in Developmental Toxicity Testing

Š. Bezek, E. Ujházy, M. Mach, J. Navarová, M. Dubovický
Developmental Origin of Chronic Diseases: Toxicological Implication

ABSTRACTS from 13th Interdisciplinary Toxicology Conference TOXCON 2008 - Trenčianske Teplice
(A-G), (G-K), (K-Z)

RJ Reiter, SD Paredes, A Korkmaz, M-J Jou, D-X Tan
Melatonin combats molecular terrorism at the mitochondrial level

J Mizerovská, H Dračínská, VM Arlt, J Hudeček, P Hodek, HH Schmeiser, E Frei, M Stiborovár
Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone

L Bořek-Dohalská, P Hodek, J Hudeček, M Stiborová
Experimental approaches to evaluate activities of cytochromes P450 3A

D Aimová, J Poljaková, V Kotrbová, M Moserová, E Frei, VM Arlt, M Stiborová
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2

M Havelková, T Randák, J Blahová, I Slatinská, Z Svobodová
Biochemical markers for the assessment of aquatic environment contamination

M Svobodová, H Dračínská, M Martínková, J Hudeček, P Hodek, E Frei, M Stiborová
Oxidation of carcinogenic 2-nitroanisole by rat cytochromes P450 – similarity between human and rat enzymes

J Poljaková, T Eckschlager, J Hřebačková, J Hraběta, M Stiborová
The comparison of cytotoxicity of the anticancer drugs doxorubicin and ellipticine to human neuroblastoma cells

B Mrázová, M Martínková, V Martínek, E Frei, M Stiborová
Optimization of preparation of apo-cytochrome b5 utilizing apo-myoglobin

J Buchancová, H Poláček, H Hudečková, L Murajda, O Osina, J Valachová
Skeletal fluorosis from the point of view of an occupational exposure to fluorides in former Czechoslovakia

M Vojtíšek, J Patková, J Knotková, L Kašparová, M Hornychová, E Frantík, J Formánek, E Švandová
Metals – impact and implications

P Doleželová, S Mácová, V Pištěková, Z Svobodová, I Bedáňová, E Voslářová
Comparison of the sensitivity of Danio rerio and Poecilia reticulata to silver nitrate in short-term tests

W Aktar, D Sengupta, S Purkait, M Ganguly, M Paramasivam
Degradation dynamics and dissipation kinetics of an imidazole fungicide (Prochloraz) in aqueous medium of varying pH

M Dubovický, P Kovačovský, E Ujházy, J Navarová, I Brucknerová, M Mach
Evaluation of developmental neurotoxicity: some important issues focused on neurobehavioral development

I Brucknerová, E Ujházy, M Dubovický, M Mach
Early assessment of the severity of asphyxia in term newborns using parameters of blood count

J Králová, M Pekarová, K Drábiková, V Jančinová, R Nosáľ, M Číž, A Lojek
The effects of dithiaden on nitric oxide production by RAW 264.7 cells

K Naiman, H Dračínská, M Dračínský, M Martínková, V Martínek, P Hodek, M Štícha, E Frei, M Stiborová
Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole

L Vilímková, J Páca Jr, V Kremláčková, J Páca, M Stiborová
Isolation of cytoplasmic NADPH-dependent phenol hydroxylase and catechol-1,2-dioxygenase from Candida tropicalis yeast

W Aktar, D Sengupta, S Purkait, A Chowdhury
Vertical migration of some herbicides through undisturbed and homogenized soil columns

A Korkmaz, H Yaren, Z I Kunak, B Uysal, B Kurt, T Topal, L Kenar, E Ucar, S Oter
Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results

W Aktar, D Sengupta, A Chowdhury
REVIEW: Impact of pesticides use in agriculture: their benefits and hazards

Ľ Mušák, V Poláková, E Halašová, O Osina, L Vodičková, J Buchancová, H Hudečková, P Vodička
Effect of occupational exposure to cytostatics and nucleotide excision repair polymorphism on chromosomal aberrations frequency

B Payal, HP Kaur, DV Rai
New insight into the effects of lead modulation on antioxidant defense mechanism and trace element concentration in rat bone

M Stiborová, K Naiman, M Martínková, V Martínek, M Svobodová, HH Schmeiser, E Frei
Genotoxic mechanisms for the carcinogenicity of the environmental pollutants and carcinogens o-anisidine and 2-nitroanisole follow from adducts generated by their metabolite N-(2-methoxyphenyl)-hydroxylamine with deoxyguanosine in DNA

M Mach, M Dubovický, J Navarová, I Brucknerová, E Ujházy
REVIEW: Experimental modeling of hypoxia in pregnancy and early postnatal life

L Bláha, P Babica, B Maršálek
Toxins produced in cyanobacterial water blooms – toxicity and risks

R Čihák
REACH – an overview

P Dvořák, M Žďárský, K Beňová
Possibilities of alternative generation II biotests at Artemia

H Modrá, Z Svobodová
Incidence of animal poisoning cases in the Czech Republic: current situation

M Pohanka
Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

P Suchý, E Straková, I Herzig, J Staňa, R Kalusová, M Pospíchalová
Toxicological risk of melamine and cyanuric acid in food and feed

J Květina
LETTER TO THE EDITOR: Reflections on changes in biomedical research ethics

14th Interdisciplinary Toxicology Conference
TOXCON 2009: Programme & Abstracts

N Kovalkovičová, I Šutiaková, J Pistl and V Šutiak
Some food toxic for pets

J Kovářová and Z Svobodová
Can thiol compounds be used as biomarkers of aquatic ecosystem contamination by cadmium?

M Tichý and M Rucki
Validation of QSAR models for legislative purposes

R Sabo, L Sabová and J Legáth
The use of parasites as bioindicators of pesticide exposure

Ľ Mušák, E Halašová, T Matáková, L Letková, L Vodičková, J Buchancová, H Hudečková, O Osina, P Souček and P Vodička
Comparison of chromosomal aberrations frequency and polymorphism of GSTs genes in workers occupationally exposed to cytostatics or anaesthetics

M Stiborová, V Martínek, M Semanská, P Hodek, M Dračínský, J Cvačka, HH Schmeiser and E Frei
Oxidation of the carcinogenic non-aminoazo dye 1-phenylazo-2-hydroxy-naphthalene (Sudan I) by cytochromes P450 and peroxidases: a comparative study

J Křížková, K Burdová, M Stiborová, V Křen and P Hodek
The effects of selected flavonoids on cytochromes P450 in rat liver and small intestine

J Hřebačková, J Poljaková, T Eckschlager, J Hraběta, P Procházka, S Smutný and M Stiborová
Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells

E Miadoková
REVIEW: Isoflavonoids – an overview of their biological activities and potential health benefits

A Korkmaz, S Oter, M Seyrek, T Topal
REVIEW: Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity

L Šoltés and G Kogan
REVIEW: Catabolism of hyaluronan: involvement of transition metals

M Moserová, V Kotrbová, D Aimová, M Šulc, E Frei, M Stiborová
Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method

E-J Yang, E-Y Yim, G Song, G-O Kim, C-G Hyun
Inhibition of nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages by Jeju plant extracts

S Bandyopadhyay and PP Choudhury
Leaching behaviour of pendimethalin causes toxicity towards different cultivars of Brassica juncea and Brassica campestris in sandy loam soil

P Sadighara, J Ashrafihelan, A Barin, TA Esfahani
Histopathology and cholinergic assessment of Pterocarya fraxinifolia on chicken embryo

M Mach
Editorial

Z Kyselova
REVIEW: Different experimental approaches in modelling cataractogenesis: An overview of selenite-induced nuclear cataract in rats

H Astroug, R Simeonova, LV Kassabova, N Danchev, D Svinarov
Pharmacokinetics of cytisine after single intravenous and oral administration in rabbits

R Simeonova, V Vitcheva, M Mitcheva
Effect of cytisine on some brain and hepatic biochemical parameters in spontaneously hypertensive rats

K Valachová, G Kogan, P Gemeiner, L Šoltés
Protective effects of manganese(II) chloride on hyaluronan degradation by oxidative system ascorbate plus cupric chloride

MA Çetinkaya, E Baydan
Investigation of in vitro effects of ethephon and chlorpyrifos, either alone or in combination, on rat intestinal muscle contraction

M Mach
Editorial

J Navarova and E Ujhazy
Obituary for Prof. Helena Rašková, MD., DSc., Dr.h.c.

V Bauer
In memory of Prof. Helena Rašková, MD., DSc., Dr.h.c.

M Stiborová, J Poljakova, T Eckschlager, R Kizek and E Frei
REVIEW: DNA and histone deacetylases as targets for neuroblastoma treatment

J Kvetina, JE Varayil, SM Ali, M Kunes, J Bures, I Tacheci, S Rejchrt, M Kopacova
REVIEW: Preclinical electrogastrography in experimental pigs

M Dubovicky
REVIEW: Neurobehavioral manifestations of developmental impairment of the brain

V Eybl, D Kotyzova
Protective effect of manganese in cadmium-induced hepatic oxidative damage, changes in cadmium distribution and trace elements level in mice

M Tichy, R Valigurova, R Cabala, R Uzlova, M Rucki
Toxicity of perfluorinated carboxylic acids for aquatic organisms

L Bartosikova, J Necas, T Bartosik, M Pavlik, P Frana
Effect of pomiferin administration on kidney ischaemia-reperfusion injury in rats

S Chen, A Vieira
A meta-analysis of medicinal plants to assess the evidence for toxicity

M Mach
Editorial

I Raška
LETTER TO EDITOR: Importance of molecular cell biology investigations in human medicine in the story of the Hutchinson-Gilford progeria syndrome

P Sobrova, V Adam, A Vasatkova, M Beklova, L Zeman, R Kizek
REVIEW: Deoxynivalenol and its toxicity

Teresa Wlasow, Krystyna Demska-Zakes, Piotr Gomulka, Sylwia Jarmolowicz
REVIEW: Various aspects of piscine toxicology

Viera Nosáľová, Ružena Sotníková, Katarína Drábiková, Silvia Fialová, Daniela Košťálová, Silvia Banášová, Jana Navarová
Chemiluminescence response induced by mesenteric ischaemia/reperfusion: effect of antioxidative compounds ex vivo

TOXCON 2010: Borderless Toxicology
Programme

TOXCON 2010: Borderless Toxicology
Abstract Book A-C

TOXCON 2010: Borderless Toxicology
Abstract Book D-M

TOXCON 2010: Borderless Toxicology
Abstract Book M-R

TOXCON 2010: Borderless Toxicology
Abstract Book R-Z

Angelika Puzserova, Iveta Bernatova
Chronic social stress increases nitric oxide-dependent vasorelaxation in normotensive rats

François-Xavier Lesage, Frédèric Deschamps, Hervé Millart
Lead levels in fur of rats treated with inorganic lead measured by inductively coupled argon plasma mass spectrometry

Zdenka Gáspárová, Oľga Ondrejičková, Alena Gajdošíková, Andrej Gajdošík, Vladimír Šnirc, Svorad Štolc
Oxidative stress induced by the Fe2+/ascorbic acid system or model ischemia in vitro: effect of carvedilol and pyridoindole antioxidant SMe1EC2 in young and adult rat brain tissue

Rajamanickam Vinodhini
Detoxifying effect of Nelumbo nucifera and Aegle marmelos on hematological parameters of Common Carp (Cyprinus carpio L.)

Petronela Žižková, Jana Viskupičová, Ľubica Horáková
Pycnogenol® and Ginkgo biloba extract: effect on peroxynitrite-oxidized sarcoplasmic reticulum Ca2+-ATPase

Miloň Tichý, Marián Rucki, Zdeněk Roth, Iveta Hanzlíková, Alena Vlková, Jana Tumová, Rút Uzlová
Extrapolation of toxic indices among test objects

Hana Střítecká, Pavol Hlubik
Selenium, zinc and magnesium: serum levels in members of the Czech Republic rescue fire brigade

Michal DUBOVICKÝ
Editorial

Juraj HARMATHA, Zdeněk ZÍDEK, Eva KMONÍČKOVÁ, Jan ŠMIDRKAL
REVIEW: Immunobiological properties of selected natural and chemically modified phenylpropanoids

Viera JANČINOVÁ, Tomáš PEREČKO, Radomír NOSÁĽ, Danica MIHALOVÁ, Katarína BAUEROVÁ, Katarína DRÁBIKOVÁ
Pharmacological regulation of neutrophil activity and apoptosis. Contribution to new strategy for modulation of inflammatory processes

Antonin LOJEK, Milan ČÍŽ, Michaela PEKAROVÁ, Gabriela AMBROŽOVÁ, Ondřej VAŠÍČEK, Jana MORAVCOVÁ, Lukáš KUBALA, Katarína DRÁBIKOVÁ, Viera JANČINOVÁ, Tomáš PEREČKO, Jana PEČIVOVÁ, Tatiana MAČIČKOVÁ, Radomír NOSÁĽ
Modulation of metabolic activity of phagocytes by antihistamines

Ružena SOTNÍKOVÁ, Jana NEDELČEVOVÁ, Jana NAVAROVÁ, Viera NOSÁĽOVÁ, Katarína DRÁBIKOVÁ, Katalin SZÖCS, Peter KŘENEK, Zuzana KYSEĽOVÁ, Štefan BEZEK, Vladimír KNEZL, Ján DŘÍMAL, Zuzana BROSKOVÁ, Viera KRISTOVÁ, Ľudmila OKRUHLICOVÁ, Iveta BERNÁTOVÁ, Viktor BAUER
REVIEW: Protection of the vascular endothelium in experimental situations

Soňa FRAŇOVÁ, Anna STRAPKOVÁ, Juraj MOKRÝ, Martina ŠUTOVSKÁ, Marta JOŠKOVÁ, Vladimíra SADLOŇOVÁ, Martina ANTOŠOVÁ, Darina PAVELČÍKOVÁ, Dana FLEŠKOVÁ, Gabriela NOSÁĽOVÁ
REVIEW: Pharmacologic modulation of experimentally induced allergic asthma

Katarína BAUEROVÁ, Silvester PONIŠT, Danica MIHALOVÁ, František DRÁFI, Viera KUNCÍROVÁ
Utilization of adjuvant arthritis model for evaluation of new approaches in rheumatoid arthritis therapy focused on regulation of immune processes and oxidative stress

Viera KRISTOVÁ, Milan KRIŠKA, Róbert VOJTKO, Miriam PETROVÁ, Silvia LÍŠKOVÁ, Radoslav VILLÁRIS, Zoltán VARGA, Martin WAWRUCH
REVIEW: Trends in vascular pharmacology research in the Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Comenius University, Bratislava

Eduard UJHÁZY, Mojmír MACH, Jana NAVAROVÁ, Ingrid BRUCKNEROVÁ, Michal DUBOVICKÝ
Safety assessment of the pyridoindole derivative SMe1EC2: developmental neurotoxicity study in rats

Svorad ŠTOLC, Lucia JAKUBÍKOVÁ, Ivica KUKUROVÁ
Body distribution of 11C-methionine and 18FDG in rat measured by microPET

Zdenka GÁSPÁROVÁ, Vladimír ŠNIRC, Svorad ŠTOLC
The new pyridoindole antioxidant SMe1EC2 and its intervention in hypoxia/hypoglycemia-induced impairment of longterm potentiation in rat hippocampus

Jana KOPINCOVÁ, Angelika PÚZSEROVÁ, Iveta BERNÁTOVÁ
REVIEW: Biochemical aspects of nitric oxide synthase feedback regulation by nitric oxide

Milan STEFEK
REVIEW: Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract

Galia ZAMARATSKAIA, Martin Krøyer RASMUSSEN, Isabelle HERBIN, Bo EKSTRAND, Vladimir ZLABEK
In vitro inhibition of porcine cytochrome P450 by 17β -estradiol and 17α-estradiol

Ivana HALUZOVÁ, Helena MODRÁ, Jana BLAHOVÁ, Marcela HAVELKOVÁ, Zuzana ŠIROKÁ, Zdeňka SVOBODOVÁ
Biochemical markers of contamination in fish toxicity tests

Anand A. ZANWAR, Mahabaleshwar V. HEGDE, Subhash L. BODHANKAR
Cardioprotective activity of flax lignan concentrate extracted from seeds of Linum usitatissimum in isoprenalin induced myocardial necrosis in rats

Marie STIBOROVÁ, Jitka POLJAKOVÁ, Eva MARTÍNKOVÁ, Lucie BOŘEK-DOHALSKÁ, Tomáš ECKSCHLAGER, Rene KIZEK, Eva FREI
Ellipticine cytotoxicity to cancer cell lines – a comparative study

TOXCON 2011 - Praha, Czech Republic
Abstract Book

Helena KANDÁROVÁ, Silvia LETAŠIOVÁ
REVIEW: Alternative methods in toxicology: pre-validated and validated methods

Ľubica HORÁKOVÁ
REVIEW: Flavonoids in prevention of diseases with respect to modulation of Ca-pump function

Areeba AHMAD, Ravish FATIMA, Veena MAHESHWARI, Riaz AHMAD
Effect of N'-nitrosodimethylamine on red blood cell rheology and proteomic profiles of brain in male albino rats

Ghada E. ELMESALLAMY, Marwa A. ABASS, Nahla A.G. Ahmed REFAT, Amal H. ATTA
Differential effects of alprazolam and clonazepam on the immune system and blood vessels of non-stressed and stressed adult male albino rats

Ashraf S. ALIAS, Muna H. I. AL-ZUBAIDY, Yaareb J. MOUSA, Fouad K. MOHAMMAD
Plasma and whole brain cholinesterase activities in three wild bird species in Mosul, IRAQ: In vitro inhibition by insecticides

Adriana SANTI, Charlene MENEZES, Marta Maria F. DUARTE, Jossiele LEITEMPERGER, Thais LÓPES, Vania L. LORO
Oxidative stress biomarkers and acetylcholinesterase activity in human erythrocytes exposed to clomazone (in vitro)

Katarína WACHALOVÁ, Jana VLKOVIČOVÁ, Veronika JAVORKOVÁ, Lucia MÉZEŠOVÁ, Peter TAKÁČ, Milan KOZÁNEK, Milan LABUDA, Patricia A. NUTTALL, Norbert VRBJAR
Effect of saliva from horse fly Hybomitra bimaculata on kinetic properties of Na,K-ATPase: possible role in regulation of relaxation

Vineet KUMAR, Gulshan ARA, Mohammad AFZAL, Yasir Hasan SIDDIQUE
Effect of methyl methanesulfonate on hsp70 expression and tissue damage in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg9

Georgeta BOCHEVA, Nadka BOYADJIEVA
REVIEW: Epigenetic regulation of fetal bone development and placental transfer of nutrients: progress for osteoporosis

Zuzana KYSELOVA
REVIEW: Toxicological aspects of the use of phenolic compounds in disease prevention

Sanjib BHATTACHARYA, Pallab Kanti HALDAR
Trichosanthes dioica root extract induces tumor proliferation and attenuation of antioxidant system in albino mice bearing Ehrlich ascites carcinoma

Viktor BAUER, Ružena SOTNÍKOVÁ, Katarína DRÁBIKOVÁ
Effects of reactive oxygen species and neutrophils on endothelium-dependent relaxation of rat thoracic aorta

Yuriy V. SOLODUN, Yulia B. MONAKHOVA, Thomas KUBALLA, Andriy V. SAMOKHVALOV, Jürgen REHM, Dirk W. LACHENMEIER
Unrecorded alcohol consumption in Russia: toxic denaturants and disinfectants pose additional risks

George Awuku ASARE, Phyllis ADDO, Kwasi BUGYEI, Ben GYAN, Samuel ADJEI, Lydia Serwaa OTU-NYARKO, Edwin Kwame WIREDU, Alexander NYARKO
Acute toxicity studies of aqueous leaf extract of Phyllanthus niruri

Natália SEDLÁČKOVÁ, Veronika PONECHALOVÁ, Eduard UJHÁZY, Michal DUBOVICKÝ, Mojmír MACH
Anxiolytic activity of pyridoindole derivatives SMe1EC2 and SMe1M2: behavioral analysis using rat model

Preeti YADAV, Sunil E. JADHAV, Vinesh KUMAR, Kirtee K. KAUL, Satish C. PANT, Swaran J.S. FLORA
Protective efficacy of 2-PAMCl, atropine and curcumin against dichlorvos induced toxicity in rats

Ganna Mykhailivna SHAYAKHMETOVA, Larysa Borysivna BONDARENKO, Valentina Mykolaivna KOVALENKO
Damage of testicular cell macromolecules and reproductive capacity of male rats following co-administration of ethambutol, rifampicin, isoniazid and pyrazinamide

Çimen KARASU, Ahmet CUMAOĞLU, Ali Rifat GÜRPINAR, Murat KARTAL, Lucia KOVACIKOVA, Ivana MILACKOVA, Milan STEFEK
Aldose reductase inhibitory activity and antioxidant capacity of pomegranate extracts

Miroslav POHANKA, Oto PAVLIS, Hana SVOBODOVA, Jiri PIKULA
Acetylcholine and an acetylcholinesterase inhibitor neostigmine can aggravate tularemia progress in BALB/c mice

Awad G. OSMAN, Ashraf M. SHERIF, Adil A. ELHUSSEIN, Afrah T. MOHAMED
Sensitivity of some nitrogen fixers and the target pest Fusarium oxysporum to fungicide thiram

Amir Ali SHAHBAZFAR, Payman ZARE, Hemn MOHAMMADPOUR, Hossein TAYEFI-NASRABADI
Effects of different concentrations of artemisinin and artemisinin-iron combination treatment on Madin Darby Canine Kidney (MDCK) cells

Issa T. SOMÉ, Abdoul K. SAKIRA, Moustapha OUÉDRAOGO, Theodore Z. OUÉDRAOGO, Adama TRAORÉ, Blaise SONDO, Pierre I. GUISSOU
Arsenic levels in tube-wells water, food, residents’ urine and the prevalence of skin lesions in Yatenga province, Burkina Faso

Adama M. TOE, Sylvain ILBOUDO, Moustapha OUEDRAOGO, Pierre I. GUISSOU
Biological alterations and self-reported symptoms among insecticides-exposed workers in Burkina Faso

Gagan FLORA, Deepesh GUPTA, Archana TIWARI
REVIEW: Toxicity of lead: A review with recent updates

Viera JANČINOVÁ, Tomáš PEREČKO, Juraj HARMATHA, Radomír NOSÁĽ, Katarína DRÁBIKOVÁ
REVIEW: Decreased activity and accelerated apoptosis of neutrophils in the presence of natural polyphenols

Katarína DRÁBIKOVÁ, Tomáš PEREČKO, Radomír NOSÁĽ, Juraj HARMATHA, Jan ŠMIDRKAL, Viera JANČINOVÁ
REVIEW: Polyphenol derivatives – potential regulators of neutrophil activity

Tatiana MAČIČKOVÁ, Jana PEČIVOVÁ, Juraj HARMATHA, Klára SVITEKOVÁ, Radomír NOSÁĽ
Effect of stilbene derivative on superoxide generation and enzyme release from human neutrophils in vitro

Jana PEČIVOVÁ, Tatiana MAČIČKOVÁ, Klára SVITEKOVÁ, Radomír NOSÁĽ
Quercetin inhibits degranulation and superoxide generation in PMA stimulated neutrophils

Tomáš PEREČKO, Katarína DRÁBIKOVÁ, Radomír NOSÁĽ, Juraj HARMATHA, Viera JANČINOVÁ
Involvement of caspase-3 in stilbene derivatives induced apoptosis of human neutrophils in vitro

Frantisek DRAFI, Katarina BAUEROVA, Viera KUNCIROVA, Silvester PONIST, Danica MIHALOVA, Tatiana FEDOROVA, Juraj Harmatha, Radomir NOSAL
Pharmacological influence on processes of adjuvant arthritis: Effect of the combination of an antioxidant active substance with methotrexate

Michal DUBOVICKÝ, Eszter CSÁSZÁROVÁ, Zuzana BRNOLIAKOVÁ, Eduard UJHÁZY, Jana NAVAROVÁ, Mojmír MACH
Effect of prenatal administration of venlafaxine on postnatal development of rat offspring

David BASKETTER, Dagmar JÍROVA and Helena KANDÁROVÁ
Review of skin irritation/corrosion hazards on the basis of human data: A regulatory perspective

Magda KOURILOVA-URBANCZIK
LETTER TO THE EDITOR: Some linguistic and pragmatic considerations affecting science reporting in English by non-native speakers of the language

Carlos Kusano Bucalen FERRARI
REVIEW: Effects of xenobiotics on total antioxidant capacity

Harold I. ZELIGER, Yaqin PAN, William J. REA
Predicting co-morbidities in chemically sensitive individuals from exhaled breath analysis

Alexey A. TINKOV, Olga P. AJSUVAKOVA, Alexandr M. SHEHTMAN, Viktor M. BOEV, Alexandr A. NIKONOROV
Influence of iron and copper consumption on weight gain and oxidative stress in adipose tissue of Wistar rats

Raquel JASPER, Gabriel Olivo LOCATELLI, Celso PILATI, Claudriana LOCATELLI
Evaluation of biochemical, hematological and oxidative parameters in mice exposed to the herbicide glyphosate-Roundup®

Daniel Francisco ARENCIBIA-ARREBOLA, Luis Alfredo ROSARIO-FERNÁNDEZ, Yolanda Emilia SUÁREZ-FERNÁNDEZ, Alexis VIDAL-NOVOA, Livan DELGADO-ROCHE
Comparison in the efficiency of different murine lines for genotoxicity assays

Monika JOHANSSON, Jana TOMANKOVA, Shengjie LI, Galia ZAMARATSKAIA
Simultaneous determination of cytochrome P450 1A, 2A and 3A activities in porcine liver microsomes

Ruzena SOTNIKOVA, Barbora BACOVA, Jana VLKOVICOVA, Jana NAVAROVA, Narcis TRIBULOVA
Sex differences in endothelial function of aged hypertriglyceridemic rats – effect of atorvastatin treatment

Gianpaolo GUZZI, Paolo D. PIGATTO, Francesco SPADARI, Caterina A.M. LA PORTA
Effect of thimerosal, methylmercury, and mercuric chloride in Jurkat T Cell Line

Eduard UJHÁZY, Mojmír MACH, Jana NAVAROVÁ, Ingrid BRUCKNEROVÁ, Michal DUBOVICKÝ
REVIEW: Teratology – past, present and future

Vasil N. ATANASOV, Silviya STOYKOVA, Yana GORANOVA, Mariana MITEWA, Svetla PETROVA
Acute toxicity of vipoxin and its components: is the acidic component an “inhibitor” of PLA2 toxicity?

Maja DJURENDIC-BRENESEL, Vladimir PILIJA, Neda MIMICA-DUKIC, Branislav BUDAKOV, Stanko CVJETICANIN
Distribution of opiate alkaloids in brain tissue of experimental animals

Yaareb J. MOUSA, Fouad K. MOHAMMAD
Effects of hydrogen peroxide on diazepam and xylazine sedation in chicks

Bhoopendra SINGH, Prakash Raj SINGH, Manoj Kumar MOHANTY
Toxicity of a plant based mosquito repellent/killer

Vivek Kumar DWIVEDI, Anuj BHATANAGAR, Manu CHAUDHARY
Protective role of ceftriaxone plus sulbactam with VRP1034 on oxidative stress, hematological and enzymatic parameters in cadmium toxicity induced rat model

Suphachai CHAROENSIN, Sirinya TAYA, Sugunya WONGPORNCHAI, Rawiwan WONGPOOMCHAI
Assessment of genotoxicity and antigenotoxicity of an aqueous extract of Cleistocalyx nervosum var. paniala in in vitro and in vivo models

Vandana PANDA, Hardik ASHAR, Sudhamani SRINATH
Antioxidant and hepatoprotective effect of Garcinia indica fruit rind in ethanolinduced hepatic damage in rodents

Michal DUBOVICKÝ
EDITORIAL

Dušan BLAŠKOVIČ, Petronela ŽIŽKOVÁ, Filip DRŽÍK, Jana VISKUPIČOVÁ, Miroslav VEVERKA, Ľubica HORÁKOVÁ
Modulation of rabbit muscle sarcoplasmic reticulum Ca2+-ATPase activity by novel quercetin derivatives

Ruzena SOTNIKOVA, Viera NOSALOVA, Jana NAVAROVA
Efficacy of quercetin derivatives in prevention of ulcerative colitis in rats

Ivana MILACKOVA, Lucia KOVACIKOVA, Miroslav VEVERKA, Ján GALLOVIC, Milan STEFEK
Screening for antiradical efficiency of 21 semi-synthetic derivatives of quercetin in a DPPH assay

Tatyana A. KOROLENKO, Thomas P. JOHNSTON, Nina I. DUBROVINA, Yana A. KISAROVA, Svetlana Ya. ZHANAEVA, Marina S. CHERKANOVA, Elena E. FILJUSHINA, Tatyana V. ALEXEENKO, Eva MACHOVA, Natalya A. ZHUKOVA
Effect of poloxamer 407 administration on the serum lipids profile, anxiety level and protease activity in the heart and liver of mice

Lucia RAČKOVÁ, Mária CUPÁKOVÁ, Anton ŤAŽKÝ, Júlia MIČOVÁ, Emil KOLEK, Daniela KOŠŤÁLOVÁ
Redox properties of ginger extracts: Perspectives of use of Zingiber officinale Rosc. as antidiabetic agent

Hamideh ABNOOS, Masoud FEREIDONI, Naser MAHDAVI-SHAHRI, Farhang HADDAD, Razieh JALAL
Developmental study of mercury effects on the fruit fly (Drosophila melanogaster)

Dindayal PATIDAR, Mithun S. RAJPUT, Nilesh P. NIRMAL, Wenny SAVITRI
Implementation and evaluation of adverse drug reaction monitoring system in a tertiary care teaching hospital in Mumbai, India

Tamanna JAHANGIR, Mohammed M. SAFHI, Sarwat SULTANA, Sayeed AHMAD
Pluchea lanceolata protects against Benzo(a) pyrene induced renal toxicity and loss of DNA integrity

Harold I. ZELIGER
REVIEW: Lipophilic chemical exposure as a cause of cardiovascular disease

Zuzana BROSKOVA, Ruzena SOTNIKOVA, Jana NEDELCEVOVA, Zsolt BAGI
Effect of a novel stobadine derivative on isolated rat arteries

Jevgenij A. KOVRIŽNYCH, Ružena SOTNÍKOVÁ, Dagmar ZELJENKOVÁ, Eva ROLLEROVÁ, Elena SZABOVÁ, Soňa WIMMEROVÁ
Acute toxicity of 31 different nanoparticles to zebrafish (Danio rerio) tested in adulthood and in early life stages – comparative study

Seyed Jalal HOSSEINIMEHR, Nayereh SHAFAGHATI, Monireh HEDAYATI
Genotoxicity induced by iodine-131 in human cultured lymphocytes

Nazia NAZAM, Mohammad Iqbal LONE, Sibhghatulla SHAIKH, Waseem AHMAD
Assessment of genotoxic potential of the insecticide Dichlorvos using cytogenetic assay

Gunasekaran KRISHNAMOORTHY, Kandaswamy SELVAKUMAR, Prabhu VENKATARAMAN, Perumal ELUMALAI, Jagadeesan ARUNAKARAN
Lycopene supplementation prevents reactive oxygen species mediated apoptosis in Sertoli cells of adult albino rats exposed to polychlorinated biphenyls

Javad ASHRAFIHELAN, Jamileh Salar AMOLI, Mehran ALAMDARI, Tahereh Ali ESFAHANI, Morteza MOZAFARI, Ali Reza NOURIAN, Ali Asghar BAHARI
Arsenic toxicosis in sheep: The first report from Iran

Rumyana SIMEONOVA, Nikolai DANCHEV
Assessment of surgical sutures Polymed® by intracutaneous irritation test in rabbits

Harold I. ZELIGER
REVIEW: Exposure to lipophilic chemicals as a cause of neurological impairments, neurodevelopmental disorders and neurodegenerative diseases

Tamer Mahmoud TAMER
REVIEW: Hyaluronan and synovial joint: function, distribution and healing

Natalia SESTAKOVA, Angelika PUZSEROVA, Michal KLUKNAVSKY, Iveta BERNATOVA
REVIEW: Determination of motor activity and anxiety-related behaviour in rodents: methodological aspects and role of nitric oxide

Silviya STOYKOVA, Yana GORANOVA, Ivayla PANTCHEVA, Vasil ATANASOV, Dobri DANCHEV, Svetla PETROVA
Hemolytic activity and platelet aggregation inhibitory effect of vipoxin’s basic sPLA2 subunit

Zoltán VARGA, Milan KRIŠKA, Viera KRISTOVÁ, Miriam PETROVÁ
Analysis of non-steroidal anti-inflammatory drug use in hospitalized patients and perception of their risk

Olamide E. ADEBIYI and Mathew O. ABATAN
Phytochemical and acute toxicity of ethanolic extract of Enantia chlorantha (oliv) stem bark in albino rats

Tarika THUMVIJIT, Waristha THUSCHANA, Doungporn AMORNLERDPISON, Yuwadee PEERAPORNPISAL, Rawiwan WONGPOOMCHAI
Evaluation of hepatic antioxidant capacities of Spirogyra neglecta (Hassall) Kützing in rats

Eun-Kee PARK, Sally K. MAK, Bruce D. HAMMOCK
Effects of cadmium chloride on mouse inner medullary collecting duct cells

Anthony SAMSEL and Stephanie SENEFF
REVIEW: Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance

Adama M. TOE, Mustapha OUEDRAOGO, Richard OUEDRAOGO, Sylvain ILBOUDO, Pierre I. GUISSOU
Pilot study on agricultural pesticide poisoning in Burkina Faso

Jacob K. AKINTUNDE, Ganiyu OBOH, Akintunde A. AKINDAHUNSI
Testicular membrane lipid damage by complex mixture of leachate from municipal battery recycling site as indication of idiopathic male infertility in rat

Miroslav POHANKA, Jakub SOBOTKA, Hana SVOBODOVA, Rudolf STETINA
Sulfur mustard induced oxidative stress and its alteration using asoxime (HI-6)

Martina MORAVCOVÁ, Antonín LIBRA, Jana DVOŘÁKOVÁ, Alena VÍŠKOVÁ, Tomáš MUTHNÝ, Vladimír VELEBNÝ, Lukáš KUBALA
Modulation of keratin 1, 10 and involucrin expression as part of the complex response of the human keratinocyte cell line HaCaT to ultraviolet radiation

Martina DANIHELOVÁ, Miroslav VEVERKA, Ernest ŠTURDÍK, Soňa JANTOVÁ
Antioxidant action and cytotoxicity on HeLa and NIH-3T3 cells of new quercetin derivatives

Jetti RAGHU, Vasudeva C. RAGHUVEER, Mallikarjuna C. RAO, Nagabhooshana S. SOMAYAJI, Prakash B. BABU
The ameliorative effect of ascorbic acid and Ginkgo biloba on learning and memory deficits associated with fluoride exposure

Lucia OLEXOVÁ, Tomáš SENKO, Peter ŠTEFÁNIK, Alžbeta TALAROVIČOVÁ, Lucia KRŠKOVÁ
Habituation of exploratory behaviour in VPA rats: animal model of autism

Rabindra N. PADHY, Nabakishore NAYAK, Shakti RATH
Antagonism at combined effects of chemical fertilizers and carbamate insecticides on the rice-field N2-fixing cyanobacterium Cylindrospermum sp. in vitro

Randa H. ELSLAHI, Awad G. OSMAN, Ashraf M. SHERIF, Adil A. ELHUSSEIN
Comparative study of the fungicide Benomyl toxicity on some plant growth promoting bacteria and some fungi in pure cultures

Sayanti PODDER, Sumedha ROY
Exposure-dependent variation in cryolite induced lethality in the nontarget insect, Drosophila melanogaster

Jevgenij A. KOVRIŽNYCH, Ružena SOTNÍKOVÁ, Dagmar ZELJENKOVÁ, Eva ROLLEROVÁ, Elena SZABOVÁ
Long-term (30 days) toxicity of NiO nanoparticles for adult zebrafish Danio rerio

Aneta BALCERCZYK, Grzegorz BARTOSZ, Joanna DRZEWINSKA, Łukasz PIOTROWSKI, Łukasz PULASKI, Milan STEFEK
Antioxidant action of SMe1EC2, the low-basicity derivative of the pyridoindole stobadine, in cell free chemical models and at cellular level

Sunita PANDE, Prabhu Narain SAXENA, Brijender BHUSHAN, Nishi SAXENA
Peripheral blood and bone marrow responses under stress of cypermethrin in albino rats

Seyedeh Nazanin SEYED SAADAT, Fahimeh MOHAMMADGHASEMI, Sina KHAJEH JAHROMI, Mohammad Amin HOMAFAR, Mostafa HAGHIRIL
Melatonin protects uterus and oviduct exposed to nicotine in mice

Todor BATAKLIEV, Vladimir GEORGIEV, Metody ANACHKOV, Slavcho RAKOVSKY, Gennadi E. ZAIKOV
REVIEW: Ozone decomposition

Monisha JAISHANKAR, Tenzin TSETEN, Naresh ANBALAGAN, Blessy B. MATHEW , Krishnamurthy N. BEEREGOWDA
REVIEW: Toxicity, mechanism and health effects of some heavy metals

Karsta LUETTICH, Yang XIANG, Anita ISKANDAR, Alain SEWER, Florian MARTIN, Marja TALIKKA, Patrick VANSCHEEUWIJCK, An BERGES, Emilija VELJKOVIC, Ignacio GONZALEZ-SUAREZ, Walter SCHLAGE, Julia HOENG, Manuel PEITSCH
Systems toxicology approaches enable mechanistic comparison of spontaneous and cigarette smoke-related lung tumor development in the A/J mouse model

Seyed Jalal HOSSEINIMEHR, Seyed Amir Hossein HOSSEINI
Radiosensitive effect of curcumin on thyroid cancer cell death induced by radioiodine-131

Min-Jin KIM, Dong Sam KIM, Hun-Seok YOON, Wook Jae LEE, Nam Ho LEE, Chang-Gu HYUN
Melanogenesis inhibitory activity of Korean Undaria pinnatifida in mouse B16 melanoma cells

Shiv Kumar YADAV, Chandra Kant MAURYA, Pradeep Kumar GUPTA, Ajai Kumar JAIN, Kumaran GANESAN, Rahul BHATTACHARYA
Synthesis and biological evaluation of some novel 1-substituted fentanyl analogs in Swiss albino mice

Rupal A. VASANT, A. V. R. L. NARASIMHACHARYA
Antidotal activity of Averrhoa carambola (Star fruit) on fluoride induced toxicity in rats

Juliana IVANOVA, Yordanka GLUHCHEVA, Sonja ARPADJAN, Mariana MITEWA
Effects of cadmium and monensin on renal and cardiac functions of mice subjected to subacute cadmium intoxication

Harold I. ZELIGER
Co-morditities of environmental diseases: A common cause

Marcia H. RATNER, David H. FARB, Josef OZER, Robert G. FELDMAN, Raymon DURSO
Younger age at onset of sporadic Parkinson’s disease among subjects occupationally exposed to metals and pesticides

Miroslav POHANKA
Postponed effect of neostigmine on oxidative homeostasis

Ahmed NEDZHIB, Silviya STOYKOVA, Vasil ATANASOV, Ivayla PANTCHEVA, Liudmil ANTONOV
Pd(II) complexes of acetylcholinesterase reactivator obidoxime

Soňa JANTOVÁ, Roman HUDEC, Stanislav SEKRETÁR, Juraj KUČERÁK, Martina MELUŠOVÁ
Salvia officinalis L. extract and its new food antioxidant formulations induce apoptosis through mitochondrial/caspase pathway in leukemia L1210 cells

Nuzhat PARVEEN, Shoeb AHMAD, G.G. Hammad A. SHADAB
Iron induced genotoxicity: attenuation by vitamin C and its optimization

Anna ZEMANČÍKOVÁ, Jozef TÖRÖK
Cardiovascular effects of high-fructose intake in rats with nitric oxide deficiency

Ganna M. SHAYAKHMETOVA, Larysa B. BONDARENKO, Anatoliy V. MATVIENKO, Valentina M. KOVALENKO
Chronic alcoholism-mediated metabolic disorders in albino rat testes

Javad ASHRAFIHELAN, Hamed EISAPOUR, Amir Mehdi ERFANI, Amir Ali KALANTARY, Jamileh Salar AMOLI, Morteza MOZAFARIO
High mortality due to accidental salinomycin intoxication in sheep

Šárka HŘIBOVÁ, Helena ZLÁMALOVÁ GARGOŠOVÁ, Milada VÁVROVÁ
Sorption ability of the soil and its impact on environmental contamination

Roman MORAVČÍK, Monika OKULIAROVÁ, Elena KOVÁČOVÁ, Michal ZEMAN
Diquat-induced cytotoxicity on Vero and HeLa cell lines: effect of melatonin and dihydromelatonin

Martina MELUŠOVÁ, Soňa JANTOVÁ, Eva HORVÁTHOVÁ
Carvacrol and rosemary oil at higher concentrations induce apoptosis in human hepatoma HepG2 cells

Jana PEČIVOVÁ, Radomír NOSÁĽ, Klára SVITEKOVÁ, Tatiana MAČIČKOVÁ
Arbutin and decrease of potentially toxic substances generated in human blood neutrophils

Michal DUBOVICKÝ, Eszter CSÁSZÁR, Kristína MELICHERČÍKOVÁ, Marcela KUNIAKOVÁ, Lucia RAČKOVÁ
Modulation of microglial function by the antidepressant drug venlafaxine

Oluwafemi Adeleke OJO, Basiru Olaitan AJIBOYE, Babatunji Emmanuel OYINLOYE, Adebola Busola OJO, Olaide Ibiwumi OLAREWAJU
Protective effect of Irvingia gabonensis stem bark extract on cadmiuminduced nephrotoxicity in rats

Miroslav POHANKA, Vitezslav VLCEK
Preparation and performance of a colorimetric biosensor using acetylcholinesterase and indoxylacetate for assay of nerve agents and drugs

Jan KOCHAN, Ľudmila SCHMIDTOVÁ, Irina SADLOŇOVÁ, Andrej MURÁNYI, Jana ZIGOVÁ, Marta MÚČKOVÁ
Hemostatic effect and distribution of new rhThrombin formulations in rats